Selected OMass Publications
Enhanced Declustering Enables Native Top-Down Analysis of Membrane Protein Complexes using Ion-Mobility Time-Aligned Fragmentation
Sokratous et al. JASMS
otargen: GraphQL-based R Package for Tidy Data Accessing and Processing From Open Targets Genetics
Feizi & Ray. Bioinformatics (2023)
Mapping the Binding Interactions between Human Gasdermin D and Human Caspase-1 Using Carbene Footprinting
Lloyd et al. JACS (2023)
Mass spectrometry captures biased signalling and allosteric modulation of a G-protein-coupled receptor
Yen et al. Nature Chemistry (2022)
High-throughput native mass spectrometry screening in drug discovery
Gavriilidou et al. Frontiers in Molecular Biosciences (2022)
Protein assemblies ejected directly from native membranes yield complexes for mass spectrometry
Chorev et al. Science (2018)
High-resolution mass spectrometry of small molecules bound to membrane proteins
Gault et al. Nature Methods (2016)
Ligand binding to a G protein–coupled receptor captured in a mass spectrometer
Yen et al. Science Advances (2017)
The role of interfacial lipids in stabilizing membrane protein oligomers
Gupta et al. Nature (2017)
PtdIns(4,5)P2 stabilizes active states of GPCRs and enhances selectivity of G-protein coupling
Yen et al. Nature (2018)
Recent Reference Publications
The solute carrier SPNS2 recruits PI(4,5)P2 to synergistically regulate transport of sphingosine-1- phosphate
Tang et al. Molecular Cell (2023)
Infrared Multiphoton Dissociation Enables Top-Down Characterization of Membrane Protein Complexes and G Protein-Coupled Receptors
Lutomski et al. Angewandte Chemie (2023)
Charge Engineering Reveals the Roles of Ionizable Side Chains in Electrospray Ionization Mass Spectrometry
Abramsson et al. JACS (2021)
A Mass-Spectrometry-Based Approach to Distinguish Annular and Specific Lipid Binding to Membrane Proteins
Bolla et al. Angewandte Chemie (2020)
State-dependent Lipid Interactions with the A2a Receptor Revealed by MD Simulations Using In Vivo-Mimetic Membranes
Song et al. Structure (2019)
Modular detergents tailor the purification and structural analysis of membrane proteins including G-protein coupled receptors
Urner et al. Nature Communications (2020)
Combining native and ‘omics’ mass spectrometry to identify endogenous ligands bound to membrane proteins
Gault et al. Nature Methods (2020)
Correlating Glycoforms of DC-SIGN with Stability Using a Combination of Enzymatic Digestion and Ion Mobility Mass Spectrometry
Yen et al. Angewandte Chemie (2020)
Detergent-free Lipodisq Nanoparticles Facilitate High-Resolution Mass Spectrometry of Folded Integral Membrane Proteins
Hoi et al. Nano Letters (2021)
Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters
Chi et al. The Embo Journal (2021)
