SCIENCE
Publications

Selected OMass Publications

Protein assemblies ejected directly from native membranes yield complexes for mass spectrometry

Dror S. Chorev, Lindsay A. Baker, Di Wu, Victoria Beilsten-Edmands, Sarah L. Rouse, Tzviya Zeev-Ben-Mordehai, Chimari Jiko, Firdaus Samsudin, Christoph Gerle, Syma Khalid, Alastair G. Stewart, Stephen J. Matthews, Kay Grünewald, Carol V. Robinson

Science, 2018, Vol. 362, Issue 6416, pp. 829-834

View Publication
High-resolution mass spectrometry of small molecules bound to membrane proteins

Joseph Gault, Joseph A C Donlan, Idlir Liko, Jonathan T S Hopper, Kallol Gupta, Nicholas G Housden, Weston B Struwe, Michael T Marty, Todd Mize, Cherine Bechara, Ya Zhu, Beili Wu, Colin Kleanthous, Mikhail Belov, Eugen Damoc, Alexander Makarov & Carol V Robinson

Nature Methods volume 13, pages333–336 (2016)

View Publication
Ligand binding to a G protein–coupled receptor captured in a mass spectrometer

Hsin-Yung Yen, Jonathan T. S. Hopper, Idlir Liko, Timothy M. Allison, Ya Zhu, Dejian Wang, Monika Stegmann, Shabaz Mohammed, Beili Wu and Carol V. Robinson

Science Advances, 2017, Vol. 3, no. 6

View Publication
The role of interfacial lipids in stabilizing membrane protein oligomers

Kallol Gupta, Joseph A. C. Donlan, Jonathan T. S. Hopper, Povilas Uzdavinys, Michael Landreh, Weston B. Struwe, David Drew, Andrew J. Baldwin, Phillip J. Stansfeld & Carol V. Robinson

Nature volume 541, pages421–424 (2017)

View Publication
PtdIns(4,5)P2 stabilizes active states of GPCRs and enhances selectivity of G-protein coupling

Hsin-Yung Yen, Kin Kuan Hoi, Idlir Liko, George Hedger, Michael R. Horrell, Wanling Song, Di Wu, Philipp Heine, Tony Warne, Yang Lee, Byron Carpenter, Andreas Plückthun, Christopher G. Tate, Mark S. P. Sansom & Carol V. Robinson

Nature volume 559, pages423–427 (2018)

View Publication

Recent Reference Publications

A Mass-Spectrometry-Based Approach to Distinguish Annular and Specific Lipid Binding to Membrane Proteins

Jani Reddy Bolla, Robin A. Corey, Cagla Sahin, Joseph Gault, Alissa Hummer, Jonathan T. S. Hopper, David P. Lane, David Drew, Timothy M. Allison, Phillip J. Stansfeld, Carol V. Robinson, Michael Landreh

Angewandte Chemie, Volume132, Issue9, 2020

View Publication
State-dependent Lipid Interactions with the A2a Receptor Revealed by MD Simulations Using In Vivo-Mimetic Membranes

Wanling Song, Hsin-Yung Yen, Carol V.Robinson, Mark S.P.Sansom

Volume 27, Issue 2, 2019, Pages 392-403

View Publication
Modular detergents tailor the purification and structural analysis of membrane proteins including G-protein coupled receptors

Leonhard H. Urner, Idlir Liko, Hsin-Yung Yen, Kin-Kuan Hoi, Jani Reddy Bolla, Joseph Gault, Fernando Gonçalves Almeida, Marc-Philip Schweder, Denis Shutin, Svenja Ehrmann, Rainer Haag, Carol V. Robinson & Kevin Pagel

Nature Communications volume 11, Article number: 564 (2020)

View Publication
Combining native and ‘omics’ mass spectrometry to identify endogenous ligands bound to membrane proteins

Joseph Gault, Idlir Liko, Michael Landreh, Denis Shutin, Jani Reddy Bolla, Damien Jefferies, Mark Agasid, Hsin-Yung Yen, Marcus J. G. W. Ladds, David P. Lane, Syma Khalid, Christopher Mullen, Philip M. Remes, Romain Huguet, Graeme McAlister, Michael Goodwin, Rosa Viner, John E.P. Syka & Carol V. Robinson

Nature Methods volume 17, pages505–508 (2020)

View Publication
Correlating Glycoforms of DC-SIGN with Stability Using a Combination of Enzymatic Digestion and Ion Mobility Mass Spectrometry

Hsin-Yung Yen, Idlir Liko, Joseph Gault, Di Wu, Weston B. Struwe, Carol V. Robinson

doi.org/10.1002/ange.202005727 2020

View Publication
Detergent-free Lipodisq Nanoparticles Facilitate High-Resolution Mass Spectrometry of Folded Integral Membrane Proteins

Kin Kuan Hoi, Juan Francisco Bada Juarez, Peter J. Judge, Hsin-Yung Yen, Di Wu, Javier Vinals, Garrick F. Taylor, Anthony Watts*, and Carol V. Robinson*

Nano Lett. 2021, 21, 7, 2824–2831

View Publication
Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters

Gamma Chi, Rebecca Ebenhoch, Henry Man, Haiping Tang, Laurence E Tremblay, Gabriella Reggiano, Xingyu Qiu, Tina Bohstedt, Idlir Liko, Fernando G Almeida, Alexandre P Garneau, Dong Wang, Gavin McKinley, Christophe P Moreau, Kiran D Bountra, Patrizia Abrusci, Shubhashish M M Mukhopadhyay, Alejandra Fernandez-Cid, Samira Slimani, Julie L Lavoie, Nicola A Burgess-Brown, Ben Tehan, Frank DiMaio, Ali Jazayeri, Paul Isenring, Carol V Robinson, Katharina L Dürr

EMBO J, 2021,40(14)

View Publication